FERULIC ACID: POTENTIAL THERAPEUTIC APPLICATIONS

  • Maria DRAGAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Catalina Daniela STAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Andreea Teodora IACOB “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Oana DRAGOSTIN Dunărea de Jos” University Galaţi
  • Lenuta PROFIRE “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

Ferulic acid is a phenolic compound that was first isolated in 1866 from the Ferula foetida resin (Apiaceae family) and was later obtained by synthesis. In nature, ferulic acid is found both in free and conjugated form. Due to its antioxidant effects ferulic acid can be used in the prevention and the therapy of diseases induced by oxidative stress, including Alzheimer's disease, diabetes mellitus, cancer, hypertension and atherosclerosis. The strong link between inflammation and oxidative stress suggests that ferulic acid can also be effective in the treatment of inflammatory conditions. Moreover, the specific ferulic acid structure also gives it a strong UV absorption capacity, making it a promising photoprotective agent.

Author Biographies

Maria DRAGAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Pharmacy
Department of Pharmaceutical Sciences (II)

Catalina Daniela STAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Pharmacy
Department of Pharmaceutical Sciences (II)

Andreea Teodora IACOB, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Pharmacy
Department of Pharmaceutical Sciences (I)

Oana DRAGOSTIN, Dunărea de Jos” University Galaţi

Faculty of Medicine and Pharmacy
Department of Pharmaceutical Science

Lenuta PROFIRE, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Pharmacy
Department of Pharmaceutical Sciences (I)

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Published
2018-06-30