• A. CIOBICA Alexandru Ioan Cuza” University, Iasi, Romania
  • C. HONCERIU Alexandru Ioan Cuza” University, Iasi, Romania
  • Al. CIOBICA Academy of Romanian Scientists, Bucuresti, Romania
  • D. COJOCARU “Alexandru Ioan Cuza” University, Iasi, Romania
  • F. TROFIN “Alexandru Ioan Cuza” University, Iasi, Romania
  • R. DOBRIN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Ioana Miruna BALMUS “Alexandru Ioan Cuza” University, Iasi, Romania
  • D. V. TIMOFTE “Grigore T. Popa” University of Medicine and Pharmacy Iasi


POSSIBLE RELEVANCE OF PHYSICAL EXERCISING IN ALZHEIMER’S DISEASE AND OTHER DEMENTIAS (Abstract): The benefits of consistent exercising, either cardiovascular, strength training or a combination of both, have been recently shown in neuropsychiatric patients such as Alzheimer’s disease and other dementia cases. In this way, an inverse relationship between cognitive impairment commonly observed in demented patients and cardiovascular fitness was demonstrated in a multitude of recent studies, which will be described and analyzed here. Moreover, several related features such as the relevance of oxidative stress, obesity and inflammation are discussed in this context. In addition, intensive muscle training was shown to be particularly effective leading to improved postural and motor response, and therefore reducing the motor impairments effects in dementia patients. Thus, the current trend in prevention is to support physical activity to delay dementia onset, knowing that physical exercising may be crucial in slowing or stopping the motor and general abilities decline in these patients.

Author Biographies

Al. CIOBICA, Academy of Romanian Scientists, Bucuresti, Romania

Department of Research, Faculty of Biology, Iasi, Romania
Center of Biomedical Research, Romanian Academy, Iasi, Romania

D. COJOCARU, “Alexandru Ioan Cuza” University, Iasi, Romania

Academy of Romanian Scientists, Bucuresti, Romania


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