PREVALENCE OF NASAL CARRIAGE OF STAPHYLOCOCCUS AUREUS WITH SPECIAL REFERENCE TO NUMBER OF METHICILLIN RESISTANCE AND ANTIMICROBIAL EVALUATION AMONG APPARENTLY PEOPLE WITH GOOD HEALTH STATUS

  • Camelia GRECU Biodev Medical Center, Iasi, Romania
  • A. GRECU Biodev Medical Center, Iasi, Romania
  • Ionela Lacramioara SERBAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • I. HURJUI “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Carmen DELIANU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Minela Aida MARANDUCA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Diana POPOVICI “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Irina GRADINARU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Mihaela MITREA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Loredana Liliana HURJUI “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

The emergence and spread of Staphylococcus aureus (S. aureus) strains that are resistant to some first line and supplementary group of antibiotics is a matter of public health importance. S. aureus is ubiquitously found in the environment as a commensal organism, but pathogenic strains of the bacterium that are resistant to some commonly available antibiotics puts antimicrobial therapy at risk. Objectives: To determine the number of nasal carriers of S. aureus among apparently healthy people from Iasi and to assess the antibiogram profile of isolated strains, with special reference to methicillin sensitivity. Material and methods: This study was conducted in Biodev Medical Center, Iasi, Romania, during 2014 - 2018, where a total of 757 apparently healthy patients (men, women and children) were tested for S. aureus infection. The samples were collected from their anterior nares and incubated on culture media for isolation and antibiotic susceptibility testing in microbiology department. The data was compiled and analyzed for the prevalence of S. aureus carriers, the number of MRSA strains and the antibiotic resistance pattern. Results and discussion: Our study has shown that from 757 people involved, 229 of them were carriers of S. aureus strains and 22 of them were MRSA strain carriers. Additionally, we found that the male / female portability ratio is similar and also the fact that the most carriers are in the group of age over 18, followed by school age people (age 8-18 years old). Conclusions: This study will help raise awareness regarding the danger of developing antibiotic resistance and in the same time also reduce or prevent self-medication and antibiotics abuse without medical recommendation.

Author Biographies

Camelia GRECU, Biodev Medical Center, Iasi, Romania

Microbiology Department

A. GRECU, Biodev Medical Center, Iasi, Romania

Microbiology Department

Ionela Lacramioara SERBAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (II)

I. HURJUI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (II)

Carmen DELIANU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (II)
 “Sf. Spiridon” County Clinical Emergency Hospital, Iasi, Romania
Central Laboratory

Minela Aida MARANDUCA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (II)
 “Sf. Spiridon” County Clinical Emergency Hospital, Iasi, Romania
Central Laboratory

Diana POPOVICI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Mother and Child Medicine

Irina GRADINARU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Dental Medicine
Department of Implantology, Removable dentures, Dental technology

Mihaela MITREA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (I)

Loredana Liliana HURJUI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Morpho-Functional Sciences (II)
 “Sf. Spiridon” County Clinical Emergency Hospital, Iasi, Romania
Central Laboratory

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Published
2018-12-27
Section
PREVENTIVE MEDICINE - LABORATORY