HELICOBACTER PYLORI - PRIETEN SAU DUȘMAN? O CONVIEȚUIRE DE SECOLE

  • Irina CIORTESCU Universitatea de Medicină și Farmacie ”Gr. T. Popa” Iași
  • Marioara STAN Universitatea de Medicină și Farmacie ”Gr. T. Popa” Iași
Keywords: HELICOBACTER PYLORI, GASTRIC CANCER, GASTRITIS

Abstract

Helicobacter pylori (H. pylori)
is the bacterium that causes the most common infection in the world. Epidemiological
studies show that over 50% of the population is infected, there are areas where virtually the
entire population present the infection since childhood. Although the stomach seems to be a
hostile environment for the development of microorganisms due to the acid pH not fit for
life, it may be infected; the first spiral organisms were described at this level as early as 1874.
These microorganisms were isolated by Waren and Marshall in 1982 and named Campylobacter
pyloridis. In 1989 Goodwin renamed the bacterium Helicobacter pylori. Helicobacter pylori is
thus a bacterium which manages to survive in gastric acid environment producing an
infection which, untreated, is likely to persist the entire life. This feature explains the high rate
in the spread of the infection. The infection manifests itself in different ways, depending on the
pathogenic strain and the host response, the majority of those infected being asimptomatic or
paucysimptomatic. The great achievement of Warren and Marshall,who were rewarded with a
Nobel prize in 2005, was to demonstrate that H. pylori can lead to gastric cancer, the bacteria
being categorized as an oncogene agent. The anti H. pylori campaign was only a step away...
and yet, the bacterium has been living in the stomach for centuries. We will try to list the pros
and cons of H. pylori infection, when and how the infection should be treated, clearly
indicating groups of patients in which eradication is absolutely mandatory.

Author Biographies

Irina CIORTESCU, Universitatea de Medicină și Farmacie ”Gr. T. Popa” Iași

Facultatea de Medicinã
Institutul de Gastroenterologie și Hepatologie Iași

Marioara STAN, Universitatea de Medicină și Farmacie ”Gr. T. Popa” Iași

Facultatea de Medicinã
Institutul de Gastroenterologie și Hepatologie Iași

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Published
2019-04-14
Section
INTERNAL MEDICINE - PEDIATRICS