COLONOSCOPIC SCREENING OF ASYMPTOMATIC FIRST-DEGREE RELATIVES OF COLORECTAL CANCER PATIENTS

  • Liliana CROITORU ”Gr.T. Popa” University of Medicine and Pharmacy Iași
  • Anca TRIFAN ”Gr.T. Popa” University of Medicine and Pharmacy Iași
  • Maria Rusu MAXIM ”Gr.T. Popa” University of Medicine and Pharmacy Iași
  • Irina GIRLEANU ”Gr.T. Popa” University of Medicine and Pharmacy Iași
  • Angela HULUB ”Gr.T. Popa” University of Medicine and Pharmacy Iași
  • Mihaela DIMACHE ”Gr.T. Popa” University of Medicine and Pharmacy Iași
  • C. STANCIU ”Gr.T. Popa” University of Medicine and Pharmacy Iași
Keywords: COLORECTAL CANCER, COLONOSCOPY, FIRSTDEGREE RELATIVE, SCREENING

Abstract

Aim: First-degree relatives of colorectal
cancer (CRC) patients are at increased risk for developing colorectal neoplasm, and
current guidelines recommend screening colonoscopy in such individuals. The aim of this
study was to evaluate the use of colonoscopy as the screening test in asymptomatic first-degree
relatives of CRC patients. Material and method: Colonoscopy was performed in 102 asymptomatic
individuals who had at least one first-degree relatives with CRC. Subjects included in
the screening program were aged between 36 and 72 years, and majority came from two
counties ( Suceava, Iaºi) located in north-eastern Romania. Results: Thirty colorectal lesions
were found in 17 individuals: two (6.6%) had adenocarcinomas, and remaining 15 patients
had 28 polypoid lesions: 14 (46.6%) adenomas, 5 (16.6%) tubulovillous adenomas, 3 (10%)
adenomas with high grade dysplasia and 6 (20%) had hyperplasic polyps. Conclusion:
Colonoscopy is a useful, feasible and safety initial screening tool for first-degree relatives of
patients with CRC.

Author Biographies

Liliana CROITORU, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

Ph.D. Student

Anca TRIFAN, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Medicine
Institute of Gastroenterology and Hepatology

Maria Rusu MAXIM, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Medicine
Institute of Gastroenterology and Hepatology

Irina GIRLEANU, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Medicine
Institute of Gastroenterology and Hepatology

Angela HULUB, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Medicine
Institute of Gastroenterology and Hepatology

Mihaela DIMACHE, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Medicine
Institute of Gastroenterology and Hepatology

C. STANCIU, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Medicine
Institute of Gastroenterology and Hepatology

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Published
2019-04-19
Section
INTERNAL MEDICINE - PEDIATRICS