• Diana Simona NEGRU S.C. S.I.E.P.C.O.F.A.R. S.A.
  • Monica DIACONESCU S.C. S.I.E.P.C.O.F.A.R. S.A.
  • Ana Maria PETCULESCU S.C. S.I.E.P.C.O.F.A.R. S.A.
  • Veronica BILD ”Gr.T. Popa” University of Medicine and Pharmacy Iași


The goals of this study were (a) to create a patient
electronic database by filling in the specially designed Patient Data Sheets (PDS) after interviewing
hypertensive patients and (b) to evaluate pharmacists opportunities for intervention in order
to improve hypertensive patients outcomes. Material and method: Pharmacists from two
Romanian chain community pharmacies interviewed all hypertensive patients that entered the
pharmacies during the study period (November December 2008) and selected 106 subjects
using several selection criteria. Pharmacists recorded in specially designed Patient Data Sheet
relevant information such as: demographic data, additional diagnostics (if any), lifestyle
behaviors and therapeutic data. The records were then transferred into an electronic database
and interpreted by the research team. Results: Hypertension (HT) as a single disease was
present in only 7 patients (6.6%), most of them being diagnosed with multiple illnesses (such
as HT and cardiovascular disease (CVD) in 25 patients, HT and dyslipidemia (DL) in 20
patients). More than half of the subjects (61.3%) declared they have adopted at least one
lifestyle modification component and almost 80% of the patients use two, three or more
antihypertensive agents in their medication. Conclusions: The high incidence of complications
among our hypertensive subjects justifies implementing blood pressure monitoring programs in
community pharmacies and requires pharmacists intervention for a better management of

Author Biography

Veronica BILD, ”Gr.T. Popa” University of Medicine and Pharmacy Iași

School of Pharmacy
Pharmacology and Clinical Pharmacy Department


1. Negru DS, Popa A. The necessity of pharmacist involvement for an efficient management of
hypertension. Farmacia 2006; 54 (3): 92-100.
2. Popa A. Educarea pacientului pentru prevenirea ºi controlul hipertensiunii arteriale. In: Zaharia V
editor. Rolul farmacistului în asistenþa bolnavului hipertensiv. Cluj-Napoca: Ed. Medicalã
Universitar㠓Iuliu Haþieganu”, 2004, 135-145.
3. *** Guidelines Sub-Committee. World Health Organization (WHO)/International Society of Hypertension
(ISH) statement on management of hypertension. J Hypertens 2003; 21: 1983-1992.
4. Mangum SA, Kraenow KR, Narducci WA. Identifying at-risk patients through community pharmacy-based
hypertension and stroke prevention screening projects. J Am Pharm Assoc 2003; 43 (1): 50-55.
5. Scala D, D’Avino M, Cozzolino S et al. Promotion of behavioral change in people with hypertension:
an intervention study. Pharm World Sci 2008; 30: 834-839.
6. *** Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood
Pressure. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation
and Treatment of High Blood Pressure – Complete Report. National Institute of Health, USA,
2004. NIH Publication No. 04-5230.
7. *** Guidelines Committee. European Society of Hypertension – European Society of Cardiology.
Guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011-1053.
8. Chabot I, Moisan J, Gregoire JP, Milot A. Pharmacist intervention program for control of
hypertension. Ann Pharmacother 2003; 37: 1186-1193.
9. Machado M, Bajcar J, Guzzo GC, Einarson TR. Sensitivity of patient outcomes to pharmacist
interventions. Part II: Systematic review and meta-analysis in hypertension management. Ann
Pharmacother 2007; 41: 1770-1781.
10. Martinez Perez SR, Armando PD, Molina Guerra AC, Pallares MM, Martinez Martinez F.
Relationship between cardiovascular risk factors and high blood pressure by community pharmacists in Spain. Pharm World Sci 2009; 31: 406-412.
11. Gondosch A. Consilierea pacientului în farmacie. In: Leucuþa SE editor. Farmacistul furnizor de
servicii de sãnãtate. Cluj-Napoca: Ed. Medicalã Universitar㠓Iuliu Haþieganu”, 2003, 109-120.
12. Zillich AJ, Sutherland JM, Kumbera PA, Carter BL. Hypertension outcomes through blood pressure
monitoring and evaluation by pharmacists (HOME Study). J Gen Intern Med 2005; 20: 1091-1096.
13. Garcao JA, Cabrita J. Evaluation of a pharmaceutical care program for hypertensive patients in
rural Portugal. J Am Pharm Assoc 2002; 42 (6): 858-864.
14. *** Legea nr 46/2003 (drepturile pacientului).
15. *** Legea nr. 677/2001 pentru protectia persoanelor cu privire la prelucrarea datelor cu caracter
personal ºi libera circulaþie a acestor date.