COLONIC TUBERCULOSIS VERSUS CROHN’S DISEASE. CASE REPORT AND REVIEW OF THE LITERATURE

  • Cristina Maria MUZÎCA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • C. STANCIU “Sf. Spiridon” Country Clinical Emergency Hospital Iasi
  • Laura HUIBAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • T. CUCIUREANU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Ana Maria SÎNGEAP “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • S. ZENOVIA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • S. CHIRIAC “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Camelia COJOCARIU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • C. V. SFARTI “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Anca TRIFAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

A 24-year-old female patient was admitted to our hospital, with a 3 months history of abdominal pain, 3 to 4 bloody stools per day, low grade fever, anorexia and weight loss. Physical examination revealed sub crepitant basilar rales and abdominal pain at medium compression. Laboratory examination identified mild anemia and an inflammatory syndrome. Colonoscopy revealed two large rectal ulcers at 4 cm above the anal verge, from which biopsy specimens were taken, and several other smaller ulcers, in rectum and sigmoid colon. The histological examination identified acid-fast-bacilli (AFB) and granulomatous inflammation. Computed tomography, chest X-ray, sputum smear for AFB and QuantiFeron test, suggested pulmonary and colonic tuberculosis (TB). After 6 months of directly observed therapy for TB, a repeat colonoscopy was performed which showed a scar at 4 cm above the anal verge at the place of the previously described largest ulcer and no other macroscopic changes in rectum and sigmoid were found.

Author Biographies

Cristina Maria MUZÎCA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

C. STANCIU, “Sf. Spiridon” Country Clinical Emergency Hospital Iasi

Institute of Gastroenterology and Hepatology

Laura HUIBAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

T. CUCIUREANU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

Ana Maria SÎNGEAP, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

S. ZENOVIA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

S. CHIRIAC, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

Camelia COJOCARIU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

C. V. SFARTI, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

Anca TRIFAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)
“Sf. Spiridon” Country Clinical Emergency Hospital Iasi
Institute of Gastroenterology and Hepatology

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Published
2020-09-30
Section
INTERNAL MEDICINE - PEDIATRICS