EPIDEMIOLOGICAL, CLINICAL AND HISTOLOGICAL CONSIDERATIONS REGARDING BASAL CELL CARCINOMA OF THE FACE

  • Oxana-Mădălina GROSU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • V. POROCH “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • P. CIOBANU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Alina MANOLE “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Natalia VELENCIUC “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

Skin cancer has become one of the most common forms of cancer in recent years. Two major categories of skin cancer have been identified: malignant melanoma (MM) and non-malignant skin cancer (NMSC). Among non-melanoma skin cancer lesions, basal cell carcinoma (BCC) is the most common, with a frequent localization in the face. Aim: The current study aims to demonstrate and confirm the frequency of BCC on the face. The increased frequency of these lesions on certain aesthetic units more exposed to the sun proves once again that ultraviolet radiation is the most important risk factor for the appearance of this skin lesion type. Material and methods: The study was performed on a group of 95 patients diagnosed with various histological forms of BCC, located in the face. The data has been collected from the observation files, the hospital's reports and eventually processed with the help of the statistical programs MS Excel 2010 and SPSS ver. 18.0. Results: The results of the study showed the most frequent affectation of females (86.3%). The elderly are most often affected (average age 71 years old). The anatomical region that BCC develops most often was the nasal pyramid (32.6%). The nodular form of BCC was the most common. Conclusions: The increased frequency of BCC on the more preeminent anatomical areas of the face, so more exposed to solar radiation shows once again the importance of avoiding exposure to ultraviolet radiation. Our study confirms the importance of epidemiological studies in detecting risk factors for various pathologies.

Author Biographies

Oxana-Mădălina GROSU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Elytis Hospital Hope Iasi

V. POROCH, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Regional Institute of Oncology Iasi
Department of Palliative Care

P. CIOBANU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

“Sf. Spiridon” County Clinical Emergency Hospital Iasi
Clinic of Plastic Surgery and Reconstructive Microsurgery

Natalia VELENCIUC, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Regional Institute of Oncology Iasi
IInd Oncologic Surgical Clinic

References

1. Apalla, Z, Lallas, A, Sotiriou, E, Lazaridou, E, Ioannides, D. Epidemiological trends in skin cancer. Dermatol Pract Concept 2017; 7: 1-6.
2. Bichakjian, C, Armstrong, A, Baum, C. Guidelines of care for the management of basal cell carcinoma. J Am Acad Dermatol 2018; 78: 540-559.
3. Ho, T, Byrne, PJ. Evaluation and initial management of the patient with facial skin cancer. Facial Plast Surg Clin North Am 2009; 17: 301-307.
4. Eskiizmir, G, Cingi, C. Nonmelanoma skin cancer of the head and neck: current diagnosis and treat-ment. Facial Plast Surg Clin North Am 2012; 20: 415-417.
5. Andrese E, Solovastru Gheuca L, Taranu T, Iancu LS. Epidemiological and pathological aspects of skin cancer in north east of Romania. Rev Med Chir Soc Med Nat Iasi 2014; 118 (2): 457-462.
6. Hallaji Z, Rahimi H., Mirshams-Shahshahani M. Comparison of risk factors of single basal cell carci-noma with multiple basal cell carcinomas. Indian J Dermatol 2011: 56: 398-402.
7. Pertea M, Grosu OM., Terinte C, Poroch V, Velenciuc N, Lunca S. Nail bed solitary neurofibroma: a case report and literature review. Medicine (Baltimore) 2019; 98(3): e 14111.
8. Popa L, Costin D. Optiuni de tratament in tumorile de unghi intern al ochiului. Rev Med Chir Soc Med Nat Iasi 2011; 115(4): 1142-1148.
9. Furdova A, Kapitanova K, Kollarova A, Dekac J. Periocular basal cell carcinoma - clinical perspectives. Oncol Rev 2020; 14(1): 420.
10. Pertea M, Velenciuc N, Poroch V, et al. Efficacy of negative pressure therapy (NPWT) in the man-agement of wounds of different etiologies. Rev Chim 2018; 69(8): 1980-1986.
11. Pertea M, Velenciuc N, Grosu O, Veliceasa B, Poroch V, Lunca S. Reconstruction of heel soft tissue defects using sensate medial plantar flap. J Mind Med Sci (JMMS) 2018; 5(2): 250-254.
12. Garcovich S, Colloca G, Sollena P, et al. Skin cancer epidemics in the elderly as emerging issue in geriatric oncology. Aging dis 2017; 8: 643-661.
13. Rogers HW, Weinstock MA, et al. Incidence estimate of nonmelanoma skin cancer in the United States 2006. Arch Dermatol 2010; 146: 283-287.
14. Leiter U, Garbe C. Epidemiology of melanoma and nonmelanoma skin cancer- the role of sunlight. Adv Exp Med Biol 2008; 624: 89-103.
15. Lomas A, Leonardi-Bee J, Bath-Hextall F. A systematic review of worldwide incidence of nonmela-noma skin cancer. Br J Dermatol 2012; 166: 1069-1080.
Published
2020-09-30