COMPLICATIONS IN ANTICOAGULATION THERAPY FOR PREGNANT WOMEN WITH MECHANICAL HEART VALVE. CASE REPORT AND REVIEW OF THE LITERATURE

  • M. ONOFRIESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • B. F. TOMA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Adina TANASE “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Mihaela TIRNOVANU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • B. M. CIUNTU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • D. V. TIMOFTE “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Larisa ANGHEL “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Loredana Maria HIMINIUC “Cuza-Vodă” Clinical Hospital of Obstetrics and Gynecology Iasi

Abstract

Aim: Bleeding complications happen more frequently in pregnant females who carry mechanical heart valves (MHVs) compared with biological prosthesis valves (BPVs). The main objective for these patients represents a rigorous and individual monitoring of the anticoagulant treatment in order to minimalize the rate of complications that may appear. We present from “Cuza-Vodă” Clinical Hospital of Obstetrics and Gynecology from Iasi, the case of a 30-year-old pregnant woman with dichorionic-diamniotic twin pregnancy, barrier of MHV, who suffered postoperative bleeding complication under guidelines recommended doses of anticoagulant. The hematoma that developed five days after the caesarian section need it surgical intervention for hemostasis correction. Conclusions: The incidence of bleeding complications is higher during pregnancy and postpartum in MHV carriers. Thrombosis or hemorrhage usually occur when the monitoring of anticoagulation is improper or when the treatment must be interrupted for different reasons.

Author Biographies

M. ONOFRIESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Mother and Child Medicine
“Cuza-Vodă” Clinical Hospital of Obstetrics and Gynecology Iasi

B. F. TOMA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Mother and Child Medicine

Adina TANASE, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Mother and Child Medicine
“Cuza-Vodă” Clinical Hospital of Obstetrics and Gynecology Iasi

Mihaela TIRNOVANU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Mother and Child Medicine
“Cuza-Vodă” Clinical Hospital of Obstetrics and Gynecology Iasi

B. M. CIUNTU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Surgery (I)

D. V. TIMOFTE, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Surgery (I)

Larisa ANGHEL, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Medical Specialties (I)

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Published
2020-09-30