SYSTEMIC COMPLICATIONS OF CHRONIC ALCOHOL CONSUMPTION. CASE-CONTROL STUDY CORPSES VERSUS SURVIVING PATIENTS

Authors

  • D.V. CRAUCIUC “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • C.I. STAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • D.A. CHIRAN “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • G. STATESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Anca SAVA “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • Diana BULGARU-ILIESCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi

DOI:

https://doi.org/10.22551/MSJ.2022.02.03

Abstract

The aim of this prospective study is to investigate the forensic cases of the Institute of Legal Medicine (ILM) Iasi compared to a group of living patients, based on chronic alcohol consumption in the past. Material and methods: The study group consisted of 120 subjects, of which 60 cadavers from ILM Iasi, alleged victims of chronic ethanol consumption, and 60 patients admitted to the Cardiology Clinic I of the “Sf. Spiridon” County Clinical Emergency Hospital from Iasi, in order to perform a case-control study. Results: The studied cases are dominated by male patients over 60 years of age, from rural areas. A cut off value of ethyl glucuronide (EtG) greater than 500 ng/ml proves to be a good predictor in the determinism of liver cirrhosis and dilated cardiomyopathy. Conclusions: Elevated levels of EtG have been shown to be a good predictor of liver cirrhosis and dilated cardiomyopathy.

Author Biographies

  • D.V. CRAUCIUC, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • C.I. STAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • D.A. CHIRAN, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • G. STATESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • Anca SAVA, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)
    “Prof. Dr. N. Oblu” Emergency Clinical Hospital, Iasi, Romania
    Department of Pathology

  • Diana BULGARU-ILIESCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

    Faculty of Medicine
    Department of Medical Specialties (III)
    Institute of Legal Medicine, Iasi, Romania

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2022-06-30

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Vol. 126 No. 2 (2022): The Medical-Surgical Journal

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INTERNAL MEDICINE - PEDIATRICS

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