ETIOLOGIC SPECTRUM OF POST-OPERATIVE MENINGITIS IN NEUROSURGERY
Postoperative meningitis is a rare neurosurgical complication with an incidence of 0.3%-1.5%. The most common pathogen in postoperative meningitis in many studies was Staphylococci, especially Staphylococcus aureus, however recent data reports increasing rates of gram-negative organisms. Material and methods: We performed a retrospective study including 32 patients, diagnosed with post-craniotomy meningitis, who underwent neurosurgery, hospitalized between 2016 and 2019 in “Sf. Parascheva” Clinical Hospital of Infectious Diseases from Iasi, in order to evaluate the presence of pathogens in cerebrospinal fluid samples. Results: The most common pathogens were Staphyloccoccus aureus, Streptococcus pneumoniae, followed by Acinetobacter speciae, Pseudomonas aeruginosa, Enteroccocus faecalis and Escherichia coli. Antibiotherapy was properly administrated according to the antibiogram. Conclusions: Early diagnosis, appropriate antibiotic treatment and an interdisciplinary approach can lead to a favorable outcome.
2. Lin TY, Chen WJ, Hsieh MK, et al. Postoperative meningitis after spinal surgery: a review of 21 cases from 20,178 patients. BMC Infect Dis 2014; 14: 220 / doi: 10.1186/1471-2334-14-220.
3. Brouwer MC, Tunkel AR, van de Beek D. Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis. Clin Microbiol Rev 2010; 14(3): 467-492.
4. Schreffler RT, Schreffler AJ, Wittler RR. Treatment of cerebrospinal fluid shunt infections: a decision analysis. The Pediatric Infectious Disease Journal 2002; 21(7): 632-636.
5. Hussein K, Bitterman R, Shofty B, Paul M, Neuberger A. Management of post-neurosurgical menin-gitis: narrative review. Clinical Microbiology and Infection 2017; 9(23): 621-628.
6. Conen A, Walti LN, Merlo A, Fluckiger U, Battegay M, Trampuz A. Characteristics and treatment outcome of cerebrospinal fluid shunt-associated infections in adults: A retrospective analysis over an 11-year period. Clin Infect Dis 2008; 47: 73-82.
7. Pintado V, Cabellos C, Moreno S, Meseguer MA, Ayats J, Viladrich PF. Enterococcal meningitis: a clinical study of 39 cases and review of the literature. Medicine (Baltimore) 2003; 82(5): 346-364.
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