THE SIGNIFICANCE OF LIFESTYLE, ASSOCIATED DISEASES, AND ANATOMICAL VARIANTS OF THE CIRCLE OF WILLIS IN THE FOR-MATION OF ANTERIOR COMMUNICATING ARTERY ANEURYSMS
Intracranial aneurysm represent a cerebrovascular disease with a relatively low incidence, but among these the most common are aneurysms developed in the anterior part of the circle of Willis (CoW). Material and methods: We collected the demographic and morphological data of the patients admitted in “Prof. Dr. N. Oblu” Emergency Clinical Hospital, Iași, Romania, with ruptured AcomA aneurysms, who later deceased and were autopsied in the Pathology Department of the same hospital, over a period of 6 years (January 2014 to December 2019), and analyzed data related to: age, gender, lifestyle (heavy smoking and alcoholism), type of anatomical variant of circle of Willis, and presence of any associated diseases. Results: We identified 7 patients with ruptured AComA aneurysm. 57.14% were male patients. The average age was 60.85 (range 34 to 69). Left posterior communicating artery (PcomA) was hypoplastic in 100% of all deceased patients. Right PComA presented hypoplasia (71.42%) or fetal type variant (28.57%). 71.42% of all cases showed anatomical variants both in the anterior and the posterior part of CoW. 66% of the female patients with AComA aneurysm presented obesity, type 2 diabetes, atherosclerotic disease and hypertension. 100% of male patients presented hypertension and atherosclerotic disease, 75% of them were chronic alcohol consumers and 50% were heavy smokers. Conclusions: The lifestyle, associated diseases, and anatomical variants of the component arteries of the circle of Willis, both from its anterior and posterior parts, could be risk factors for the formation of anterior communicating artery aneurysm.
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