EFFICACY OF COMPUTER-ASSISTED COGNITIVE STIMULATION IN PSYCHIATRIC DISORDERS: CORRELATIONS BETWEEN DIAGNOSIS, TREATMENT AND EVOLUTION OF COGNITIVE SCORES

Authors

  • Andreea-Catalina MOROSAN ‟Grigore Popa” University of Medicine and Pharmacy Iași
  • G. C. MOROSAN ‟Grigore Popa” University of Medicine and Pharmacy Iași
  • Carmen Gabriela LUPUSORU “Socola” Institute of Psychiatry Iasi, Romania
  • Ana-Maria DUMITRESCU ‟Grigore Popa” University of Medicine and Pharmacy Iași
  • Lucia Corina DIMA COZMA ‟Grigore Popa” University of Medicine and Pharmacy Iași
  • G. DASCALESCU “Alexandru Ioan Cuza” University Iasi / Faculty of Biology
  • A. CIOBICA “Alexandru Ioan Cuza” University Iasi / Faculty of Biology
  • Roxana CHIRITA “Socola” Institute of Psychiatry Iasi, Romania

DOI:

https://doi.org/10.22551/qmh8aa60

Abstract

This study aims to investigate the effectiveness of computer-assisted cognitive stimulation (CACS) in improving cognitive deficits associated with psychiatric disorders. Materials and methods: The study evaluated the impact of the CACS intervention on cognitive functions using standardized instruments such as the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). In addition, the influence of diagnosis and demographic variables on the results obtained was analyzed, highlighting significant variations depending on the typology of the psychiatric disorder treated. Results: The data indicate considerable improvements in the cognitive domain, with differences between diagnostic groups highlighting the importance of a differentiated approach. Conclusions: The results support the need for personalization of interventions and highlight the relevance of assessing qualitative factors in the application of CACS, opening new research directions for optimizing the treatment of psychiatric disorders through cognitive technology. 

Author Biographies

  • Andreea-Catalina MOROSAN, ‟Grigore Popa” University of Medicine and Pharmacy Iași

    Faculty of Medicine
    Department of Medical Specialties (I)
    “Socola” Institute of Psychiatry Iasi, Romania

  • G. C. MOROSAN, ‟Grigore Popa” University of Medicine and Pharmacy Iași

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • Ana-Maria DUMITRESCU, ‟Grigore Popa” University of Medicine and Pharmacy Iași

    Faculty of Medicine
    Department of Morpho-Functional Sciences (I)

  • Lucia Corina DIMA COZMA, ‟Grigore Popa” University of Medicine and Pharmacy Iași

    Faculty of Medicine
    Department of Medical Specialties (I)

  • G. DASCALESCU, “Alexandru Ioan Cuza” University Iasi / Faculty of Biology

    Department of Molecular and Experimental Biology

  • A. CIOBICA, “Alexandru Ioan Cuza” University Iasi / Faculty of Biology

    Department of Molecular and Experimental Biology
    Romanian Academy / Centre of Biomedical Research
    Academy of Romanian Scientists

References

1. Fisekovic S, Memic A, Pasalic A. Correlation between MoCA and MMSE for the assessment of cogni-tion in schizophrenia. Acta Informatica Medica 2012; 20(3): 186-189.

2. Videnovic A, Bernard B, Jaglin J, Shannon KM. The Montreal cognitive assessment as a screening tool for cognitive dysfunction in Huntington’s disease. Movement Disorders 2010; 25(3): 401-404.

3. Coyle H, Traynor V, Solowij N. Computerized and virtual reality cognitive training for individuals at high risk of cognitive decline: Systematic review of the literature. American Journal of Geriatric Psy-chiatry 2015; 23(4): 335-359.

4. Chou KL, Lenhart A, Koeppe RA, Bohnen NI. Abnormal MoCA and normal range MMSE scores in Parkinson disease without dementia: Cognitive and neurochemical correlates. Parkinsonism Relat Dis-ord 2014; 20(10): 1076-1080.

5. Bowie CR, Bell MD, Fiszdon JM, et al. Cognitive remediation for schizophrenia: An expert working group white paper on core techniques. Schizophrenia Research. 2020; 215: 49-53.

6. Chen L, Huang J, Wang S, et al. Effect of Carotid Artery Morphological Variations on Cognitive Func-tion. Behavioral Neurology 2018; 2018.

7. Hayashi H, Sone T, Iokawa K, et al. Effects of computerized cognitive training on biomarker responses in older adults with mild cognitive impairment: A scoping review. Vol. 7, Health Science Reports. John Wiley and Sons Inc, 2024.

8. Desai R, Leung WG, Fearn C, John A, Stott J, Spector A. Effectiveness of Cognitive Stimulation Therapy (CST) for mild to moderate dementia: A systematic literature review and meta-analysis of randomized control trials using the original CST protocol. Vol. 97, Ageing Research Reviews. Elsevier Ireland Ltd, 2024.

9. Rock PL, Roiser JP, Riedel WJ, Blackwell AD. Cognitive impairment in depression: A systematic review and meta-analysis. Psychological Medicine 2014; 44: 2029-2040.

10. Shamsi S, Lau A, Lencz T, et al. Cognitive and symptomatic predictors of functional disability in schiz-ophrenia. Schizophr Res 2011; 126(1-3): 257-264.

11. Wood L, Williams C, Billings J, Johnson S. A systematic review and meta-analysis of cognitive behav-ioral informed psychological interventions for psychiatric inpatients with psychosis. Schizophrenia Re-search 2020; 222: 133-144.

12. Fett AKJ, Viechtbauer W, Dominguez M de G, Penn DL, van Os J, Krabbendam L. The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: A meta-analysis. Neuroscience and Biobehavioral Reviews 2011; 35: 573-588.

13. Carvalho JCN, Donat JC, Brunnet AE, Silva TG, Silva GR, Kristensen CH. Cognitive, Neurobiological and Psychopathological Alterations Associated with Child Maltreatment: A Review of Systematic Re-views. Child Indicators Research 2016; 9: 389-406.

14. Schuwerk T, Langguth B, Sommer M. Modulating functional and dysfunctional mentalizing by tran-scranial magnetic stimulation. Front Psychol 2014; 5: 1309 / doi: 10.3389/fpsyg.2014.01309.

15. Agarwal S, Presciutti A, Verma J, et al. Women have worse cognitive, functional, and psychiatric outcomes at hospital discharge after cardiac arrest. Resuscitation 2018; 125: 12-15.

16. Downar J, Blumberger DM, Daskalakis ZJ. The Neural Crossroads of Psychiatric Illness: An Emerging Target for Brain Stimulation. Trends in Cognitive Sciences 2016; 20: 107-120.

17. Cimpianu CL, Strube W, Falkai P, Palm U, Hasan A. Vagus nerve stimulation in psychiatry: a systematic review of the available evidence. Journal of Neural Transmission 2017; 124: 145-158.

18. Warden D, Sanchez K, Greer T, et al. Demographic and clinical characteristics of current comorbid psychiatric disorders in a randomized clinical trial for adults with stimulant use disorders. Psychiatry Res. 2016; 246: 136-41.

19. Nieman DH, Chavez-Baldini U, Vulink NC, et al. Protocol across study: Longitudinal transdiagnostic cognitive functioning, psychiatric symptoms, and biological parameters in patients with a psychiatric disorder. BMC Psychiatry 2020; 20(1): 212 / doi: 10.1186/ s12888-020-02624-x.

20. Peters SK, Dunlop K, Downar J. Cortico-striatal-thalamic loop circuits of the salience network: A cen-tral pathway in psychiatric disease and treatment. Vol. 10, Frontiers in Systems Neuroscience. Frontiers Media S.A. 2016.

21. Demirtas-Tatlidede A, Vahabzadeh-Hagh AM, Pascual-Leone A. Can noninvasive brain stimulation enhance cognition in neuropsychiatric disorders? Neuropharmacology 2013; 64: 566-578.

22. Sheth SA, Bijanki KR, Metzger B, et al. Deep Brain Stimulation for Depression Informed by Intracranial Recordings. Biol Psychiatry 2022; 92(3): 246-251.

23. Matsuda Y, Yamazaki R, Shigeta M, Kito S. Transcranial magnetic stimulation modalities for psychiat-ric disorders: Publication trends from 1985 to 2019. Neuro-psychopharmacol Rep 2021; 41(4): 538-543.

Additional Files

Published

2025-04-07

Issue

Vol. 129 No. 1 (2025): The Medical-Surgical Journal

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INTERNAL MEDICINE - PEDIATRICS

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