SPINAL METASTASES IN THE MOST COMMON CANCERS
DOI:
https://doi.org/10.22551/79nf6y53Abstract
The aims of this study are to identify the underlying causes of spinal injuries and the molecular subtypes which are involved in the production of these pathologies. Materials and methods: This study is a retrospective one, which covered a period of four months (from January 1st to April 30th, 2015), and involved a total of 50 patients who were diagnosed with non-traumatic spinal cord injuries. These patients received treatment at the “Prof. Dr. N. Oblu” Emergency Clinical Hospital in Iași. Results: Despite having a group of just 50 patients we also managed to identify several key factors implicated in bone dissemination of the primary tumor: skeletal homotropism, vertebral bone composition, genetic and epigenetic alterations, bone remodeling imbalance. Conclusions: The study highlights the need for a multidisciplinary approach to manage spinal metastases effectively. The interplay between cancer progression, bone health, and patient’s quality of life, can help healthcare providers to develop more comprehensive management strategies for individuals affected by metastatic disease.
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