STUDY ON THE IMPACT OF DIODE LASER ON POSTOPERATIVE EVOLUTION IN ORAL SURGERY
DOI:
https://doi.org/10.22551/MSJ.2025.04.16Abstract
Aim of study was to compare the clinical postoperative evolution in the treatment of gingival hyperplasia by using diode laser and scalpel surgery. Materials and methods: A total of 40 patients with gingival hyperplasia, selected from the Clinical Learning Base of the Faculty of Dental Medicine, Grigore T. Popa University of Medicine and Pharmacy Iasi, were included in study. Participants were divided in test group (laser-assisted surgery, n = 20) and control group (scalpel surgery, n = 20). The laser surgery was performed with Epic (BioLase) (940 nm). Postoperative evolution was assessed at 24 hours, 3 days, and 7 days. The postoperative evolution was assessed by the progression of the postoperative pain intensity (Visual Analogue Scale) and healing time (days). Results: For gingivectomy performed with diode laser, mean VAS scores decreased from 2.60 ± 0.38 days at 24 h to 0.21 ± 0.22 at 7 days (p < 0.001) versus 5.20 ± 0.77 days (at 24 h) to 1.20 ± 0.64 (7 days) in the scalpel group (p < 0.001). Mean healing times were significantly shorter after laser therapy (3.20 ± 0.77 days) compared to scalpel surgery (8.40 ± 2.09). Conclusions: Laser-assisted surgery lead to faster healing time and accelerates the decrease of postoperative pain intensity during first 7 days posttreatment, compared to traditional surgical approach.
References
1. Convissar RA. Principles and Practice of Laser Dentistry. 2nd edition; Mosby Elsevier: St. Louis, MO, USA, 2016.
2. Agop-Forna D, Sălceanu M, Topoliceanu C, Creţu C, Vasincu D, Forna N. Dental lasers in restorative dentistry: A review. Romanian Journal of Oral Rehabilitation 2021; 13(2): 7-17.
3. Noba C, Mello-Moura ACV, Gimenez T, Tedesco TK, Moura-Netto C. Laser for bone healing after oral surgery: systematic review. Lasers Med Sci 2018; 33(3): 667-674.
4. Saydjari Y, Kuypers T, Gutknecht N. Laser Application in Dentistry: Irradiation Effects of Nd: YAG 1064 Nm and Diode 810 Nm and 980 Nm in Infected Root Canals-A Literature Overview. Biomed Res Int 2016; 2016: 8421656.
5. Saleh HM, Saafan AM. Excision Biopsy of Tongue Lesions by Diode Laser. Photomed. Laser Surg 2007; 25: 45-49.
6. Farronato D, Fumagalli D, Asa’ad F, Rasperini G. Decontamination of Customized Laser-Microtextured Titanium Abutments: A Comparative in Vitro Study of Different Cleaning Procedures. Int J Periodontics Restor Dent 2018; 38: 87-95.
7. He M, Zhang B, Shen N, Wu N, Sun J. A Systematic Review and Meta-Analysis of the Effect of Low-Level Laser Therapy (LLLT) on Chemotherapy-Induced Oral Mucositis in Pediatric and Young Patients. Eur. J. Pediatr 2018; 177: 7-17.
8. Takahashi K, Onoda C, Sugiyama S, Noro A, Makiishi T, Ishikawa T. Clinical evaluation of Ga-Al-As semiconductor laser diode (UNI-LASER) irradiation in treatment of solitary aphtha, erosion and hypersensitive dentin. Shikwa Gakuho 1987; 87: 295-303.
9. 9.Derikvand N, Chinipardaz Z, Ghasemi S, Chiniforush N. The Versatility of 980 Nm Diode Laser in Dentistry: A Case Series. J Lasers Med Sci 2016; 7: 205-208.
10. Verma SK, Maheshwari S, Singh RK, Chaudhari PK. Laser in Dentistry: An Innovative Tool in Mod-ern Dental Practice. Natl J Maxillofac Surg 2012; 3: 124-132.
11. Sobouti F, Khatami M, Heydari M, Barati M. The role of low-level laser in periodontal surgeries. J Lasers Med Sci 2015; 6(2): 45-50.
12. Nadhreen AA, Alamoudi NM, Elkhodary HM. Low-level laser therapy in dentistry: Extra-oral appli-cations. Niger J Clin Pract 2019; 22(10): 1313-1318.
13. Enwemeka CS. Laser biostimulation of healing wounds: specific effects and mechanisms of action. J Orthop Sports Phys Ther 1988; 9(10): 333-338.
14. Reddy GK, Stehno-Bittel L, Enwemeka CS. Laser photostimulation of collagen production in healing rabbit Achilles tendons. Lasers Surg Med 1998; 22(5): 281-287.
15. Friedmann H, Lubart R, Laulicht I, Rochkind S. A possible explanation of laser-induced stimulation and damage of cell cultures. J Photochem Photobiol B 1991; 11(1): 87-91.
16. Grossman N, Schneid N, Reuveni H, Halevy S, Lubart R. 780 nm low power diode laser irradiation stimulates proliferation of keratinocyte cultures: Involvement of reactive oxygen species. Lasers Surg Med 1998; 22(4): 212-218.
17. Chrepa V, Kotsakis GA, Pagonis TC, Hargreaves KM. The effect of photodynamic therapy in root canal disinfection: A systematic review. J Endod 2014; 40(7): 891-898.
18. Mylona V, Anagnostaki E, Chiniforush N, Barikani H, Lynch E, Grootveld M. Photobiomodulation effects on periodontal ligament stem cells: A systematic review of in-vitro studies. Curr Stem Cell Res Ther 2024; 19(4): 544-558.
19. Mussttaf RA, Jenkins DFL, Jha AN. Assessing the impact of low-level laser therapy (LLLT) on biological systems: a review. Int J Radiat Biol 2019; 95(2): 120-143.
20. Chintavalakorn R, Saengfai NN, Sipiyaruk K. The Protocol of Low-level Laser Therapy in Orthodontic Practice: A Scoping Review of Literature. J Int Soc Prev Community Dent 2022; 12(3): 267-286.
21. Abdulhadi A, Burhan AS, Hajeer MY, Hamadah O, Mahmoud G, Nawaya FR, et al. Evaluation of the Functional Treatment of Patients with Skeletal Class II Malocclusion Using Low-Level Laser Therapy-Assisted Twin-Block Appliance: A Three-Arm Randomized Controlled Trial. Cureus 2022; 14(3): e23449.
22. Zhang OL, Yin IX, Yu OY, et al. Advanced Lasers and Their Applications in Dentistry. Dent J (Basel) 2025; 13(1): 37 / doi: 10.3390/dj13010037.
23. Aldelaimi TN, Khalil AA. Clinical Application of Diode Laser (980 nm) in Maxillofa-cial Surgical Procedures. J Craniofac Surg 2015; 26(4): 1220-1223.
24. Kazakova R, Tomov G, Vlahova A, et al. Assessment of Healing after Diode Laser Gingiv-ectomy Prior to Prosthetic Procedures. Applied Sciences 2023; 13(9): 5527 / doi: 10.3390/app13095527.
25. Maboudi A, Fekrazad R, Shiva A, et al. Gingivectomy with Diode Laser Versus the Conventional Scalpel Surgery and Nonsurgical Periodontal Therapy in Treatment of Orthodontic Treatment-Induced Gingival Enlargement: A Systematic Review. Photo biomodul Photomed Laser Surg 2023; 41(9): 449-459.
26. Abesi F, Derikvand N. Efficacy of Low-Level Laser Therapy in Wound Healing and Pain Reduction After Gingivectomy: A Systematic Review and Meta-analysis. J Lasers Med Sci 2023; 14: e17 / doi: 10.34172/jlms.2023.17.
27. Yakout BK, Kamel FR, Khadr MAEA, Heikal LAH, El-Kimary GI. Efficacy of hyaluronic acid gel and photobiomodulation therapy on wound healing after surgical gingivectomy: a randomized controlled clinical trial. BMC Oral Health 2023; 23(1): 805 / doi: 10.1186/ s12903-023-03519-5.
28. Hanna R, Pawelczyk-Madalińska M, Sălăgean T, Nap ME, Bordea IR, Benedicenti S. A Novel Con-cept of Combined High-Level-Laser Treatment and Transcutaneous Photobiomodulation Therapy Utilisation in Orthodontic Periodontal Interface Management. Sensors (Basel) 2022; 22(6): 2263 / doi: 10.3390/s22062263.
29. Zhao H, Hu J, Zhao L. The effect of low-level laser therapy as an adjunct to periodontal surgery in the management of postoperative pain and wound healing: a systematic review and meta-analysis. Lasers Med Sci 2021; 36(1): 175-187.
30. Kim HR, Son K, Son YT, et al. A Comparative Immunohistochemical Study of Wound Healing after Dental Diode Laser Treatment in the Rat Oral Mucosa. Bioengineering (Basel) 2022; 9(9): 466.
31. D'Arcangelo C, Di Nardo Di Maio F, Prosperi GD, et al. A preliminary study of healing of diode laser versus scalpel incisions in rat oral tissue: a comparison of clinical, histological, and immuno-histochemical results. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007; 103(6): 764-773.
32. Mahler P, Allard Y, Rocca Jean-Paul. Lasers and Prosthetics. In: Oral Implantology (editors Fornaini C, Rocca JP). Editografica, EdLearning, 2015.
Additional Files
Published
Issue
Section
License
Copyright (c) 2025 The Medical-Surgical Journal
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
COPYRIGHT
Once an article is accepted for publication, MSJ requests a transfer of copyrights for published articles.
COPYRIGHT TRANSFER FORM FOR
REVISTA MEDICO-CHIRURGICALĂ A SOCIETĂȚII DE MEDICI ȘI NATURALIȘTI DIN IAȘI /
THE MEDICAL-SURGICAL JOURNAL OF THE SOCIETY OF PHYSICIANS AND NATURALISTS FROM IASI
We, the undersigned authors of the manuscript entitled
_____________________________________________________________________________________
_____________________________________________________________________________________
warrant that this manuscript, which is submitted for publication in the REVISTA MEDICO-CHIRURGICALĂ, has not been published and it is not under consideration for publication in another journal.
- we give the consent for publication in the REVISTA MEDICO-CHIRURGICALĂ, in printed and electronic format and we transfer unconditioned and complete the copyright of this manuscript to the REVISTA MEDICO-CHIRURGICALĂ, in the event of its acceptance.
- the manuscript does not break the intellectual property rights of any other person.
- we have read the submitted version of the manuscript and we are fully responsible for the content.
Names and signatures of authors / copyright owners (the following sequence is the authorship of the article):
- ______________________________/_________________________
- ______________________________/_________________________
- ______________________________/_________________________
N.B. All the authors must sign this form
