DEMOGRAPHIC AND CLINICAL FEATURES WITH SURGICAL CONSIDERATIONS IN ADULT CRANIOPHARYNGIOMAS: A ROMANIAN NEUROSURGICAL CENTER EXPERIENCE

Authors

  • Ana-Marina RĂDULESCU Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Anca SAVA Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Ana-Maria DUMITRESCU Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • L. EVA Prof. Dr. N. Oblu Emergency Clinical Hospital, Iasi, Romania
  • Gabriela Florența DUMITRESCU Prof. Dr. N. Oblu Emergency Clinical Hospital, Iasi, Romania
  • D. ROTARIU Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • Veronica SCRIPCARU Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • A. D. CHIRAN Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania
  • C. I. STAN Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

DOI:

https://doi.org/10.22551/MSJ.2026.02.17

Abstract

Craniopharyngiomas (CPs) are rare benign epithelial tumors of the sellar-suprasellar region that remain surgically challenging. Aim: To evaluate the clinical, imaging, pathological and surgical aspects of CPs diagnosed in adult patients as such previous analyses are rare. Materials and methods: We performed a retrospective study that included adult patients (≥18 years) with surgical treated and pathologically confirmed CP between January 2016 and December 2021. Eligible cases were analyzed regarding demographic data, clinical presentation, and surgical approach. Results: Eleven adult patients were included (mean age 46.6 ± 12.6 years), with a slight female predominance (54.5%). Two peaks in patients’ age were noted: one in the fifth decade of life (40- to 49-year-olds) and another in the seventh decade of life (60- to 69-year-olds). Visual disturbances were the most frequent presenting symptom (81.8%), but headache (54.5%), endocrine disfunctions (36.36%), and neurocognitive symptoms (27.3%) were also identified. Open craniotomy was performed in 72.7% of cases, while extended endoscopic endonasal approach was realized in the rest of the cases. Subtotal resection was achieved in 63.6% of all cases. Conclusions: The findings of our study align with published data, while highlighting specific diagnostic peculiarities in Romanian adult patients with craniopharyngiomas.

Author Biographies

  • Anca SAVA, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Prof. Dr. N. Oblu Emergency Clinical Hospital, Iasi, Romania

  • L. EVA, Prof. Dr. N. Oblu Emergency Clinical Hospital, Iasi, Romania

    Dunărea de Jos University Galați, Romania

  • D. ROTARIU, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Prof. Dr. N. Oblu Emergency Clinical Hospital, Iasi, Romania

  • Veronica SCRIPCARU, Grigore T. Popa University of Medicine and Pharmacy Iasi, Romania

    Prof. Dr. N. Oblu Emergency Clinical Hospital, Iasi, Romania

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Additional Files

Published

2026-06-01

Issue

Vol. 130 No. 2 (2026): The Medical-Surgical Journal

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PREVENTIVE MEDICINE - LABORATORY

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