INCIDENCE OF PRIMARY CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH ERECTILE DYSFUNCTION
Aim: Identification of primary cardiovascular risk factors in patients with erectile dysfunction. Material and methods: The study included 308 apparently healthy men, with a mean age of 45±12.1 years. The Sexual Health Inventory for Men (SHIM) questionnaire was used to determine the following indices: BMI, blood pressure, blood glucose, cholesterol, triglycerides, etc. Results: The total incidence of cardiovascular risk factors was 56%: 45% in men aged up to 40 years (group I) and 74% in those over 40 years (group II). High blood pressure was found in 9% of the men in group I and 55% in those in group II (p <0.05). Blood glucose levels were recorded in 5% of group I patients 24% in group II patients. Sixty-six percent of the men over 40 years were overweight compared with 16% of men under age 40. Dyslipidemia was present in 65% of group I versus 19% in group II. Conclusions: Our study shows that especially in men over 40 years of age erectile dysfunction is a vascular endothelial condition clearly associated with cardiovascular risk factors; the direct association between the severity of erectile dysfunction and increased levels of cardiovascular risk factors reflects their importance in the occurrence and course of the disease, which should be taken into account when diagnosing an erectile dysfunction and selecting the therapeutic approach.
2. Wespes E., Eardley I., Giuliano F. et al. Guidelines on Male Sexual Dysfunction: Erectile dysfunction and premature ejaculation. European Association of Urology. Amsterdam. 2013; http://uroweb.org/wp-content/uploads/14_Male-Sexual Dysfunction_LR.pdf. Accessed: 04.12.2017.
3. Feldman H.A, Goldstein I., Hatzichristou D.G. et al. Impotence and Its Medical and Psychosocial Correlates: Results of the Massachusetts Male Aging Study, J. Urol. 1994; 151(1): 54-61.
4. Braun M., Wassmer G., Klotz T., Reifenrath B., Mathers M., Engelmann U. Epidemiology of erectile dysfunction: results of the ‘Cologne Male Survey’. Int. J. Impot. Res. 2000; 12: 305-311.
5. Doumas M., Tsakiris A., Douma Stella, et al. Factors Affecting the Increased Prevalence of Erectile Dysfunction in Greek Hypertensive Compared With Normotensive Subjects. J. Androl. 2006; 27 (3): 469-477.
6. Hodges L.D, Kirby M., Solanki J., O'Donnell J. & Brodie D.A. The temporal relationship between erectile dysfunction and cardiovascular disease. Internat. J. Clin. Pract. 2007; 61: 2019–2025.
7. Montorsi P., Montorsi F., Schulman C.C. Is erectile dysfunction the “tip of the iceberg” of a systemic vascular disorder? Eur. Urol 2003; 44(3): 352–354.
8. Gandaglia G., Briganti A., Jackson G. et al. A Systematic Review of the Association Between Erectile Dysfunction and Cardiovascular Disease. Europ. Urol 2014; 65(5): 968-978.
9. Standards of Medical Care in Diabetes. American Diabetes Association. Diabetes Care 2011; 34: 4-10.
10. Caproş N., Barbacar N., Istrati V., Branişte T. Aspects of the molecular-genetic profile in patients with ischemic heart disease. Rev. Med. Chir. Soc. Med. Nat. Iasi 2013; 117(1): 78-82.
11. Branishte T., Braniște A. Coronary circulation and cardiac hemodynamics – morpho functional and immunohistochemical particularities in patients with ischemic heart disease. Rev. Med. Chir. Soc. Med. Nat. Iasi 2017; 121(1): 41-45.
12. Montrosi P., Ravaghani P., Galli S. et al. Association between erectile dysfunction and coronary artery dissease. Role of coronary clinical presentation and extent of coronary vessels involvement. The COBRA trial. Eur. Heart. J 2006; 27(22): 2632-2639.
13. Nehra A., Jacson G., Miner M. et al. The Princeton III Consensus recommendations for the manage-ment of erectile dysfunction and cardiovascular disease. Mayo. Clinic. Proc. 2012; 87: 766-778.
14. Catapano AL, Graham I, De Backer G. et al. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias. Europ. Heart J 2016; 37 (39): 2999 – 3058.
15. Dahabreh I, Paulus J. Association of episodic physical and sexual activity with triggering of acute cardiac events: systematic review and meta-analysis. JAMA 2011; 305(12): 1225-1233.
Once an article is accepted for publication, MSJ requests a transfer of copyrights for published articles.
The copyright form will be signed by the corresponding author.
COPYRIGHT TRANSFER FORM FOR REVISTA MEDICO-CHIRURGICALĂ A SOCIETĂȚII DE MEDICI ȘI NATURALIȘTI DIN IAȘI
THE MEDICAL-SURGICAL JOURNAL OF THE SOCIETY OF PHYSICIANS AND NATURALISTS FROM IASI
We, the undersigned authors of the manuscript entitled
this manuscript, which is submitted for publication in the REVISTA MEDICO-CHIRURGICALĂ, has not been published and it is not under consideration for publication in another journal.
- we give the consent for publication in the REVISTA MEDICO-CHIRURGICALĂ, in printed and electronic format and we transfer unconditioned and complete the copyright of this manuscript to the REVISTA MEDICO-CHIRURGICALĂ, in the event of its acceptance.
- the manuscript does not break the intellectual property rights of any other person.
- we have read the submitted version of the manuscript and we are fully responsible for the content.
Names and signatures of authors / copyright owners (the following sequence is the authorship of the article):
N.B. All the authors must sign this form