CIRCULATING TUMOR CELLS IN RECTAL CANCER PATIENTS – A REVIEW OF THE LITERATURE

  • D.V. SCRIPCARIU “Grigore T. Popa” University of Medicine and Pharmacy Iasi
  • C.D. LUPASCU “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Abstract

Rectal cancer treatment has been continuously improving in the past decades and research has rightly been directed for this purpose, because this is a major public health issue. On the other hand, circulating tumor cells have emerged in the past two decades as an important element in oncology, because of the large potential they offer. They have been studied mostly in breast cancer and have already been implemented as a tool in certain strategies in this field. Thus, circulating tumor cells in rectal cancer may have the same important applicability, with a wide range of usages, from screening to diagnostics, guidance of the treatment and even follow-up. This article aims to review the literature and exhibit data about the pathophysiology, utility and methods of identification of circulating tumor cells with focus on their link to rectal cancer.

Author Biographies

D.V. SCRIPCARIU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Surgery (I)
Regional Institute of Oncology Iasi
First Surgical Unit

C.D. LUPASCU, “Grigore T. Popa” University of Medicine and Pharmacy Iasi

Faculty of Medicine
Department of Surgery (I)
“Sf. Spiridon” County Clinical Emergency Hospital Iasi
Second Surgical Unit

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Published
2018-04-04